Severe obstructive sleep apnea increases left atrial volume independent of left ventricular diastolic impairment

Left ventricular diastolic dysfunction is linked to severity of obstructive sleep apnea Running head: diastole and sleep apnea

Word count: 199) Background Obstructive sleep apnea has been related to increased cardiovascular risk. The present study examined the relationships between respiratory parameters and left ventricular abnormalities in obstructive sleep apnea. Patients/Methods One hundred and fifty newly diagnosed OSA patients without any known cardiovascular disease were included (age = 49±11 years, BMI = 27.1±3...

Subclinical Left Ventricular Dysfunction in Patients with Obstructive Sleep Apnea

OBJECTIVE We aimed to investigate whether fragmented QRS (fQRS) is associated with subclinical left ventricular (LV) dysfunction in patients with obstructive sleep apnea (OSA). SUBJECTS AND METHODS A total of 141 patients with OSA who had normal LV ejection fraction (LVEF) were included in the study. The fQRS was defined as the presence of an additional R wave, notching of R or S wave or the ...

Impact of left ventricular diastolic dysfunction on left atrial volume and function: a volumetric analysis.

AIMS Diastolic dysfunction may result in elevation of left ventricular (LV) and atrial pressures, resulting in left atrial (LA) remodelling. We examined the effects of LV diastolic dysfunction on LA volume and function. METHODS AND RESULTS We measured LA volume and function in 83 patients with normal LV systolic function. The LV diastolic function grade was defined using traditional Doppler m...

Diastolic dysfunction and left atrial volume

OBJECTIVES We examined the association between diastolic function and left atrial volume indexed to body surface area (LAVi) in a population-based study. BACKGROUND Atrial enlargement has been suggested as a marker of the severity and duration of diastolic dysfunction (DD). However, the association between DD and atrial enlargement and their individual prognostic implications in the population ...

Left ventricular diastolic dysfunction in atrial fibrillation